产品
编 号:F070303
分子式:C23H18N6O2
分子量:410.43
产品类型
结构图
CAS No: 1206101-20-3
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生物活性:
GLPG0634 analog (Compoun 176) is a broad spectrum JAK inhibitor with IC50 values of <100 nM against JAK1, JAK2 and JAK3.
体外研究:
GLPG0634 analog (Compoun 176) inhibits JAK-STAT signaling and OSM/IL-lβ signaling with both EC50 values of 101-500 nM.GLPG0634 analog shows microsomal stability of 76%-100% in rat and human.