产品
编 号:F741385
分子式:C17H22N4O2
分子量:314.38
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
Ralmitaront (RO6889450) is an orally active agonist of trace amine-associated receptor 1 (TAAR1) with a EC50 value of 110.4 nM. Ralmitaront has antipsychotic, cognitively improvement, and antidepressant activity in rodents. Ralmitaront can be used as a neurosuppressant in the study of neuro-related diseases, such as schizophrenia (SCZ), schizoaffective disorder.

体外研究:
Ralmitaront (0-30 μM, 70 min) 在 TAAR1 上表现出比 Ulotaront 更低的功效和更慢的结合动力学,而在 5-HT1AR 和 D2 R 上,Ralmitaront 缺乏明显的活性。
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