产品
编 号：F741383
分子式：C20H19F6N7O2
分子量：503.4
分子式：C20H19F6N7O2
分子量：503.4
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 2130996-00-6
产品详情
生物活性：
GLPG2938 is a potent and selective S1P2 antagonist. GLPG2938 can be used for the research of idiopathic pulmonary fibrosis.
体内研究：
GLPG2938 (1~10 mg/kg; p.o.) displays a marked protective effect at all dosed tested, resulting in statistically significant reduction of the Ashcroft score.GLPG2938 shows good pharmacokinetics, with long half-life, low clearance, and good bioavailability in all species, especially in dogs.Animal Model:Male C57BL/6 mice
Dosage:1~10 mg/kg
Administration:P.o.
Result:Displayed a marked protective effect at all dosed tested, resulting in statistically significant reduction of the Ashcroft score.?
体外研究：
GLPG2938 (0.5~5 μM; HPF cells) significantly prevents the S1P-mediated contraction at all tested concentrations.
GLPG2938 is a potent and selective S1P2 antagonist. GLPG2938 can be used for the research of idiopathic pulmonary fibrosis.
体内研究：
GLPG2938 (1~10 mg/kg; p.o.) displays a marked protective effect at all dosed tested, resulting in statistically significant reduction of the Ashcroft score.GLPG2938 shows good pharmacokinetics, with long half-life, low clearance, and good bioavailability in all species, especially in dogs.Animal Model:Male C57BL/6 mice
Dosage:1~10 mg/kg
Administration:P.o.
Result:Displayed a marked protective effect at all dosed tested, resulting in statistically significant reduction of the Ashcroft score.?
体外研究：
GLPG2938 (0.5~5 μM; HPF cells) significantly prevents the S1P-mediated contraction at all tested concentrations.
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