产品
编 号:F741370
分子式:C28H26N2O12P2
分子量:644.46
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with an IC50 of 82 nM and 1.7 μM for STAT5b and STAT5a, respectively. Stafib-2 exhibits poor cell permeability.

体外研究:
Stafib-2 has an extremely high affinity for STAT5b (Ki=8.8 nM).Stafib-2 (3-10 μM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells.
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