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编 号:F741348
分子式:C26H21ClF4N6O4
分子量:592.93
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM.

体内研究:
Asundexian 在人和兔血浆中显示出强大的体外抗凝活性,在兔动脉血栓形成模型中显示出体内抗血栓形成功效。
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