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编 号:F741334
分子式:C19H25N5O3
分子量:371.43
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2/4 and PB1(5), with Kds of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3), with Kds of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts.

体外研究:
SGC-SMARCA-BRDVIII (化合物 22) (1 μM;14 天) 阻断 3T3-L1 鼠成纤维细胞中的脂肪细胞分化。
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