产品
编 号:F741311
分子式:C22H20ClN5O3S
分子量:469.94
产品类型
结构图
CAS No: 1887069-10-4
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产品详情
生物活性:
Gamcemetinib (CC-99677) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). Gamcemetinib is extracted from patent WO2020236636, compound 1.
体外研究:
Gamcemetinib 是一种有效的、共价的、不可逆的丝裂原活化蛋白 (MAP) 激酶-活化蛋白激酶-2 (MK2) 通路抑制剂,在生化 (IC 50=156.3 nM) 和基于细胞的检测 (EC50=89 nM)。