产品
编 号:F741310
分子式:C21H18FN3O2
分子量:363.38
产品类型
结构图
CAS No: 1885900-35-5
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产品详情
生物活性:
Antiproliferative agent-14 (compound 3b) a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle.
体外研究:
Antiproliferative agent-14 (compound 3b) shows antiproliferative activity against HeLa cell (IC50=13 nM).Antiproliferative agent-14 shows inhibition of colchicine binding activity, with 72.2% inhibitory percentage.