产品
编 号：F741283
分子式：C30H33N3
分子量：435.6
分子式：C30H33N3
分子量：435.6
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 1807631-83-9
产品详情
生物活性：
CJJ300 is a transforming growth factor-β (TGF-β) inhibitor with an IC50 of 5.3 μM. CJJ300 inhibits TGF-β signaling by disrupting the formation of the TGF-β-TβR-I-TβR-II signaling complex.
体外研究：
CJJ300 disturbs protein-protein interactions and prevents TGF-β receptor dimerization (IC50 = 23.6 ± 5.8 μM).CJJ300 (0-80 μM, 2 h) inhibits the phosphorylation of intracellular mediators in the downstream TGF-β signaling pathways, and suppresses the expression of markers of EMT (epithelial-mesenchymal transition) without cytotoxicity.CJJ300 suppresses TGF-β induced cell migration.
CJJ300 is a transforming growth factor-β (TGF-β) inhibitor with an IC50 of 5.3 μM. CJJ300 inhibits TGF-β signaling by disrupting the formation of the TGF-β-TβR-I-TβR-II signaling complex.
体外研究：
CJJ300 disturbs protein-protein interactions and prevents TGF-β receptor dimerization (IC50 = 23.6 ± 5.8 μM).CJJ300 (0-80 μM, 2 h) inhibits the phosphorylation of intracellular mediators in the downstream TGF-β signaling pathways, and suppresses the expression of markers of EMT (epithelial-mesenchymal transition) without cytotoxicity.CJJ300 suppresses TGF-β induced cell migration.
产品资料
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