产品
编 号：F741248
分子式：C18H18ClFN2O3
分子量：364.8
分子式：C18H18ClFN2O3
分子量：364.8
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CAS No: 1629615-99-1
产品详情
生物活性：
ALDH2 modulator 1 is a potent and orally active aldehyde dehydrogenase-2 (ALDH2) modulator. ALDH2 modulator 1 reduces blood alcohol levels in mice.
体内研究：
ALDH2 modulator 1 (compound 161) (10 mg/kg for i.v.; 40, 60 mg/kg for p.o.) 降低经口服 5 g/kg 酒精处理的小鼠的血液酒精水平。Animal Model:8-9 weeks, 20-22 g, Male C57BL6 mice (treated with PO 5/kg of EtOH)
Dosage:40, 60 mg/kg for p.o. or 10 mg/kg for i.v.
Administration:P.o. or i.v.
Result:Reduced blood alcohol levels in mice treated with PO 5 g/kg of EtOH.
ALDH2 modulator 1 is a potent and orally active aldehyde dehydrogenase-2 (ALDH2) modulator. ALDH2 modulator 1 reduces blood alcohol levels in mice.
体内研究：
ALDH2 modulator 1 (compound 161) (10 mg/kg for i.v.; 40, 60 mg/kg for p.o.) 降低经口服 5 g/kg 酒精处理的小鼠的血液酒精水平。Animal Model:8-9 weeks, 20-22 g, Male C57BL6 mice (treated with PO 5/kg of EtOH)
Dosage:40, 60 mg/kg for p.o. or 10 mg/kg for i.v.
Administration:P.o. or i.v.
Result:Reduced blood alcohol levels in mice treated with PO 5 g/kg of EtOH.
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