产品
编 号：F741204
分子式：C22H21F3N4O4S
分子量：494.49
分子式：C22H21F3N4O4S
分子量：494.49
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 1425485-87-5
产品详情
生物活性：
Uplarafenib (B-Raf IN 10) (Compound C09) is a BRAF inhibitor with an IC50 between 50 and 100 nM. Uplarafenib shows antitumor activity.
体外研究：
Uplarafenib (Compound C09) (1 μM) shows more than 89% inhibition against BRAF and BRAF V600E.Uplarafenib shows an IC50 between 50 and 100 nM against BRAF, less than 50 nM against BRAF V600E.Uplarafenib (72 h) inhibits A375 and SK-MEL-28 cells growth but not CHL-1 and SK-MEL-31 cells.
Uplarafenib (B-Raf IN 10) (Compound C09) is a BRAF inhibitor with an IC50 between 50 and 100 nM. Uplarafenib shows antitumor activity.
体外研究：
Uplarafenib (Compound C09) (1 μM) shows more than 89% inhibition against BRAF and BRAF V600E.Uplarafenib shows an IC50 between 50 and 100 nM against BRAF, less than 50 nM against BRAF V600E.Uplarafenib (72 h) inhibits A375 and SK-MEL-28 cells growth but not CHL-1 and SK-MEL-31 cells.
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