产品
编 号:F741123
分子式:C23H36ClN3O4
分子量:454
产品类型
结构图
CAS No: 1202400-18-7
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产品详情
生物活性:
BMS-817399 is a potent, selective, and orally bioavailable CCR1 antagonist. BMS-817399 exhibits CCR1 binding affinity and chemotaxis inhibition potencies of 1 and 6 nM (IC50), respectively. BMS-817399 can be used for the research of rheumatoid arthritis.
体外研究:
In addition to MIP-1α (CCL3), BMS-817399 potently inhibits chemotaxis induced by other CCR1 ligands.