产品
编 号：F740953
分子式：C14H10ClN5O
分子量：299.72
分子式：C14H10ClN5O
分子量：299.72
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CAS No: 651769-78-7
产品详情
生物活性：
Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia.
体内研究：
Xanthine oxidoreductase-IN-3 (化合物 IIIa) (5 mg/kg; 口服给药) 在给药后 3 h 显示出降低急性高尿酸血症小鼠尿酸的作用。Animal Model:ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthine
Dosage:5 mg/kg
Administration:Suspended in 0.5% CMC-Na solution for intragastric administration
Result:Showed a uric acid-lowering effect from 3 h after administration.
Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia.
体内研究：
Xanthine oxidoreductase-IN-3 (化合物 IIIa) (5 mg/kg; 口服给药) 在给药后 3 h 显示出降低急性高尿酸血症小鼠尿酸的作用。Animal Model:ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthine
Dosage:5 mg/kg
Administration:Suspended in 0.5% CMC-Na solution for intragastric administration
Result:Showed a uric acid-lowering effect from 3 h after administration.
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