产品
编 号:F740947
分子式:C22H20N2O2
分子量:344.41
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5mg
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10mg
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25mg
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50mg
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100mg
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产品详情
生物活性:
TASK-1-IN-1 is a potent and selective TASK-1 (Potassium Channel) inhibitor with an IC50 of 148 nM. TASK-1-IN-1 shows a reduced inhibition of TASK-3 channels (IC50 of 1750 nM) and not a significant effect on other K+ channels. TASK-1-IN-1 has anticancer effects.

体外研究:
TASK-1-IN-1 (compound F3) blocks cell proliferation and viability in the MCF-7 cancer cell line but not in TASK-1 knockdown MCF-7 cells, indicating that it is acting in TASK-1 channels.
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