产品
编 号:F740899
分子式:C18H28N2O2S
分子量:336.49
产品类型
结构图
CAS No: 407587-01-3
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产品详情
生物活性:
ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells.
体外研究:
ANO1-IN-1 (Compound 9c) (10 μM) significantly suppresses migration and invasion of U251 cells.ANO1-IN-1 and TMZ combination brings about remarkable synergistic effects in suppressing proliferation of GBM cells.