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编 号:F740869
分子式:C20H22N4O
分子量:334.41
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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生物活性:
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).

体外研究:
BVDV-IN-1 (compound 1.9) binds to a hydrophobic pocket of the BVDV RNA-dependent RNA polymerase (RdRp).BVDV-IN-1 inhibits the replication of TSC-resistant BVDV variants in vitro.
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