产品
编 号:F740859
分子式:C11H8ClN5O4
分子量:309.67
产品类型
结构图
CAS No: 329227-30-7
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产品详情
生物活性:
L82 is a selective and uncompetitive DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM). L82 shows anti-proliferative activity to breast cancer cells.
体外研究:
L82 (0-50 μM; 6 d) shows anti-proliferative activity to breast cancer cells.L82 (50 μM; 0-48 h) shows cytostatic activity due to activation of the G1/S checkpoint in MCF7 cells.