产品
编 号：F740839
分子式：C23H18O4
分子量：358.39
分子式：C23H18O4
分子量：358.39
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规格
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结构图
CAS No: 307552-53-0
产品详情
生物活性：
SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea.
体外研究：
SLC26A3-IN-1 (化合物4a) (10 μM; 10 min) 对 SLC26A3 的抑制率为 87%。
SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea.
体外研究：
SLC26A3-IN-1 (化合物4a) (10 μM; 10 min) 对 SLC26A3 的抑制率为 87%。
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