产品
编 号：F740790
分子式：C19H18N2O2
分子量：306.36
分子式：C19H18N2O2
分子量：306.36
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CAS No: 186610-88-8
产品详情
生物活性：
hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific agents.
体外研究：
hVEGF-IN-2 (0-100 μM) shows the inhibitory activities to particular RTKs at the cellular level with IC50 values of 2.5, 33.1, ＞100, ＞100 and ＞100 nM for VEGF, PDGF, EGF, HER-2 and IGF-1, respectively.
hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific agents.
体外研究：
hVEGF-IN-2 (0-100 μM) shows the inhibitory activities to particular RTKs at the cellular level with IC50 values of 2.5, 33.1, ＞100, ＞100 and ＞100 nM for VEGF, PDGF, EGF, HER-2 and IGF-1, respectively.
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