产品
编 号:F736989
分子式:C21H22N6OS2
分子量:438.57
产品类型
结构图
CAS No: 522650-91-5
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产品详情
生物活性:
SIRT2-IN-9 (compound 12) is a selective inhibitor of SRIT2 with an IC50 value of 1.3 μM. SIRT2-IN-9 inhibits proliferative activity of MCF-7 breast cancer cells. SIRT2-IN-9 can be used for the research of cancer.
体外研究:
SIRT2-IN-9 (1-100 μM; 15 min) dose-dependently inhibits SRIT2 with an IC50 value of 1.3 μM, and inhibits SRIT1 and SRIT3 with IC50s >300 μM.SIRT2-IN-9 (0-50 μM; 72 h) affects cell viability of MCF-7 cells.SIRT2-IN-9 (0-50 μM; 6 h) affects acetylation of α-tubulin protein.