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编 号:F069073
分子式:C21H19N5O2S
分子量:405.47
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CAS No: 1203479-63-3
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SRTCX1002 is a potent activator of SIRT1 (STAC), suppresses inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB Activity. SRTCX1002 suppresses stimuli-induced NF-κB transcriptional activation and LPS-induced TNFα secretion with IC50s of 0.71 and 7.58 μM, respectively.