产品
编 号：F735561
分子式：C99H182F3N37O21
分子量：2283.78
分子式：C99H182F3N37O21
分子量：2283.78
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2828432-37-5
产品详情
生物活性：
COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC50 of 445 nM.
体内研究：
COG 133 (1 mg/kg; intratracheal administration; every other day; for 4 weeks) treatment impairs the resolution of pulmonary fibrosis in mice.Animal Model:Male C57BL/6 mice (6-week-old) instilled with Bleomycin
Dosage:1 mg/kg
Administration:Intratracheal administration; every other day; for 4 weeks
Result:Did blunt the resolution of lung fibrosis.
COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC50 of 445 nM.
体内研究：
COG 133 (1 mg/kg; intratracheal administration; every other day; for 4 weeks) treatment impairs the resolution of pulmonary fibrosis in mice.Animal Model:Male C57BL/6 mice (6-week-old) instilled with Bleomycin
Dosage:1 mg/kg
Administration:Intratracheal administration; every other day; for 4 weeks
Result:Did blunt the resolution of lung fibrosis.
产品资料
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