产品
编 号:F722549
分子式:C14H19NO4S
分子量:297.37
产品类型
结构图
CAS No: 35619-65-9
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产品详情
生物活性:
Trithiozine is an orally active antisecretory and antiulcer agent. Trithiozine can be used for the research of peptic ulcer disease and hypersecretory disorders.
体内研究:
Trithiozine (T) (i. p., oral, i. v.; 50 mg/kg, 200 mg/kg) shows a considerable antisecretory and antiulcer activity on different experimental models in the rats and dogs.Animal Model:female Sprague-Dawley rats and male beagle dogs
Dosage:50 mg/kg (rats); 200 mg/kg or 50 mg/kg (dogs)
Administration:i. p., single (rats); oral, single or i. v. (dogs)
Result:Showed an apparent plasma half-life of about 2.5 h in rats and 1 h in dogs and rapidly metabolized yielding two metabolites and two conjugates.