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编 号：F719323
分子式：C8H17NO5S2
分子量：271.35
分子式：C8H17NO5S2
分子量：271.35
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CAS No: 94161-07-6
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生物活性：
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound 109Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication.
体内研究：
N-methyl-N-dithiocarboxyglucamine (684-2736 mg/kg；腹腔注射，每日注射 3 次) 3 天内有效促进粪便镉排泄。N-methyl-N-dithiocarboxyglucamine (2736 mg/kg；腹腔注射，每周注射 3 次) 降低肾脏和肝脏的镉水平。Animal Model:Mice with CdCl2 injection
Dosage:684, 1368 and 2736 mg/kg
Administration:Intraperitoneal injection; 684, 1368 and 2736 mg/kg, three daily injection
Result:Dose-dependently increased fecal Cd excretion and caused a fecal Cd excretion of almost 30% of the administered Cd over a 3-day period at a dose of 2736 mg/kg.
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound 109Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication.
体内研究：
N-methyl-N-dithiocarboxyglucamine (684-2736 mg/kg；腹腔注射，每日注射 3 次) 3 天内有效促进粪便镉排泄。N-methyl-N-dithiocarboxyglucamine (2736 mg/kg；腹腔注射，每周注射 3 次) 降低肾脏和肝脏的镉水平。Animal Model:Mice with CdCl2 injection
Dosage:684, 1368 and 2736 mg/kg
Administration:Intraperitoneal injection; 684, 1368 and 2736 mg/kg, three daily injection
Result:Dose-dependently increased fecal Cd excretion and caused a fecal Cd excretion of almost 30% of the administered Cd over a 3-day period at a dose of 2736 mg/kg.
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