产品
编 号:F719003
分子式:C20H29F2N3O2S
分子量:413.52
产品类型
结构图
CAS No: 881413-29-2
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产品详情
生物活性:
AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pKi values of 7.93 and 9.06 for human CB1R and CB2R, respectively. AZD1940 shows a robust analgesia action.
体内研究:
When given orally to rats, AZD1940 produces a robust analgesia in different models of inflammatory and neuropathic pain.For AZD1940, low brain uptake at analgesic doses has been demonstrated in both rats and primates.
体外研究:
AZD1940 binds with high affinity to human, rat and mouse CB1 and CB2 receptors and displays full agonism at both receptors in all three species.