产品
编 号:F717592
分子式:C35H31ClN5O7PS2
分子量:764.21
产品类型
结构图
CAS No: 615538-47-1
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产品详情
生物活性:
DC4SMe, a phosphate proagent of cytotoxic DNA alkylator DC4, can be used in the synthesis of antibody-drug conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer.
体外研究:
The phosphate prodrug may be a suitable choice for ADCs of effector molecules that do not possess sufficient water solubility or stability.