产品
编 号：F716846
分子式：C26H26N4O5
分子量：474.51
分子式：C26H26N4O5
分子量：474.51
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CAS No: 534605-74-8
产品详情
生物活性：
TP3011 (CH0793011) is an active metabolite of CH-0793076 and is a potent?topoisomerase I?inhibitor equipotent as SN38. TP3011 is against cancer cell lines growth with IC50s at the range sub-nanomolar in vitro.
体外研究：
TP3011 (0-100 nM; 72 hours) (compound 6c) inhibits cell proliferative activities against various human cancer cell lines, producing 50% inhibition (IC50) of cell growth of 0.85 nM; 8.5 nM; and 8.2 nM inHCT116, QG56, and NCI-H460 (NSCLC) cells, respectively.
TP3011 (CH0793011) is an active metabolite of CH-0793076 and is a potent?topoisomerase I?inhibitor equipotent as SN38. TP3011 is against cancer cell lines growth with IC50s at the range sub-nanomolar in vitro.
体外研究：
TP3011 (0-100 nM; 72 hours) (compound 6c) inhibits cell proliferative activities against various human cancer cell lines, producing 50% inhibition (IC50) of cell growth of 0.85 nM; 8.5 nM; and 8.2 nM inHCT116, QG56, and NCI-H460 (NSCLC) cells, respectively.
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