产品
编 号：F715446
分子式：C22H13F3N6O
分子量：434.37
分子式：C22H13F3N6O
分子量：434.37
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2416022-90-5
产品详情
生物活性：
DDR1-IN-5 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 7.36 nM. DDR1-IN-5 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 4.1 nM. DDR1-IN-5 has anti-cancer activity. DDR1-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体外研究：
DDR1-IN-5 (compound 121; for 24 hours) inhibits collagen production in human hepatic stellate cell LX-2 (IC50=62 nM). DDR1-IN-5 (72 hours) has cytotoxicity in LX-2 cells (CC50>40 μM).
DDR1-IN-5 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 7.36 nM. DDR1-IN-5 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 4.1 nM. DDR1-IN-5 has anti-cancer activity. DDR1-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体外研究：
DDR1-IN-5 (compound 121; for 24 hours) inhibits collagen production in human hepatic stellate cell LX-2 (IC50=62 nM). DDR1-IN-5 (72 hours) has cytotoxicity in LX-2 cells (CC50>40 μM).
产品资料
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