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编 号:F715440
分子式:C21H20N2O3
分子量:348.4
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants.

体外研究:
EMI56 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI56 can be used in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC).EMI56 (10, 15, 20 μM; 2?h of treatment) strongly inhibits total EGFR levels, activation and downstream signaling in PC9 EGFR ex19del/T790M/C797S cells.
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