产品
编 号:F715426
分子式:C25H22Cl2FN5O
分子量:498.38
产品类型
结构图
CAS No: 2407457-36-5
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生物活性:
WDR5-IN-4 is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a Kd of 0.1 nM. WDR5-IN-4 displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity.