产品
编 号:F715367
分子式:C28H50N4O4
分子量:506.72
产品类型
结构图
CAS No: 2355185-12-3
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产品详情
生物活性:
Antitumor agent-23 is a potent anti-cancer agent with GI50s of 38, 48, 5, 27, 80, and 28 nM for lymphoma cell line GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI, respectively. Antitumoral activity.
体外研究:
Antitumor agent-23 (0.001-100 μM; 5 days) inhibits lymphoma cells proliferation.Antitumor agent-23 (2-70 nM; 72 hours) induces p53 protein expression and p53 lysine 382 acetylation (K382Ac-p53) in HPV-positive cervical cancer cell.