产品
编 号：F715350
分子式：C18H18BrNO4
分子量：392.24
分子式：C18H18BrNO4
分子量：392.24
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CAS No: 2326007-49-0
产品详情
生物活性：
IV-23 (Compound 20) is a potent Noxa mediated apoptosis inducer, and it is a promising anticancer agent with potential. IV-23 inhibits cell growths in vitro and in vivo, reduces colony formation, arrests cell cycle at M phase, and induces esophageal squamous cell carcinoma (ESCC).
体外研究：
IV-23 (Compound 20) shows a strong inhibition against the ESCCs in a concentration depend manner, the IC50 values against the Kyse30 and Kyse450 cell lines were all less than 2?μM, presented in a dose-dependent manner. IV-23 triggeres caspases related apoptosis in ESCC cells. IV-23 induces G2/M phase arrest.
IV-23 (Compound 20) is a potent Noxa mediated apoptosis inducer, and it is a promising anticancer agent with potential. IV-23 inhibits cell growths in vitro and in vivo, reduces colony formation, arrests cell cycle at M phase, and induces esophageal squamous cell carcinoma (ESCC).
体外研究：
IV-23 (Compound 20) shows a strong inhibition against the ESCCs in a concentration depend manner, the IC50 values against the Kyse30 and Kyse450 cell lines were all less than 2?μM, presented in a dose-dependent manner. IV-23 triggeres caspases related apoptosis in ESCC cells. IV-23 induces G2/M phase arrest.
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