产品
编 号:F715285
分子式:C26H25N3O7S2
分子量:555.62
产品类型
结构图
CAS No: 2260542-60-5
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产品详情
生物活性:
OSMI-2 (Compound 1b) is a cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-2 increases detained intron splicing in cells.
体外研究:
OSMI-2 (Compound 1b; 20-50 μM; 4-24 hours; HCT116 cells) treatment reduces O-GlcNAc levels at short treatment times (OSMI-2 相关抗体:Western Blot AnalysisCell Line:HCT116 cells
Concentration:20 μM, 40 μM, 50 μM
Incubation Time:4 hours, 24 hours
Result:Reduced O-GlcNAc levels.