产品
编 号：F715266
分子式：C22H23ClF3N5O
分子量：465.9
分子式：C22H23ClF3N5O
分子量：465.9
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 2250019-95-3
产品详情
生物活性：
NVS-PAK1-C is a potent,?ATP-competitive and specific allosteric PAK1 inhibitor probe with IC50 values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 (IC50=270 nM) and phosphorylated PAK2 (IC50=720 nM).
体外研究：
NVS-PAK1-1?potently inhibits autophosphorylation of PAK1 (S144) at 0.25 μM in the Su86.86 cell line and MEK S289 phosphorylation with an IC50=0.21 μM in Su86.86 cells in which PAK2 is downregulated.
NVS-PAK1-C is a potent,?ATP-competitive and specific allosteric PAK1 inhibitor probe with IC50 values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 (IC50=270 nM) and phosphorylated PAK2 (IC50=720 nM).
体外研究：
NVS-PAK1-1?potently inhibits autophosphorylation of PAK1 (S144) at 0.25 μM in the Su86.86 cell line and MEK S289 phosphorylation with an IC50=0.21 μM in Su86.86 cells in which PAK2 is downregulated.
产品资料
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