产品
编 号：F715222
分子式：C30H37F3N2O6
分子量：578.62
分子式：C30H37F3N2O6
分子量：578.62
产品类型
规格
价格
是否有货
结构图
CAS No: 2222264-64-2
产品详情
生物活性：
GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM. GLPG-3221 can be uesd for the treatment of cystic fibrosis.
体内研究：
GLPG-3221 (1 mg/kg; i.v.) treatment shows the?Cl and?t1/2?are 0.13 L/h/kg and?3?hours,?respectively.GLPG-3221 (1 mg/kg; p.o.)treatment shows the F% value is 53%.Animal Model:Rat?
Dosage:1 mg/kg
Administration:i.v. administration?(Pharmacokinetic?Analysis)
Result:The?Cl and?t1/2?were 0.13 L/h/kg and?3?hours,?respectively.
GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM. GLPG-3221 can be uesd for the treatment of cystic fibrosis.
体内研究：
GLPG-3221 (1 mg/kg; i.v.) treatment shows the?Cl and?t1/2?are 0.13 L/h/kg and?3?hours,?respectively.GLPG-3221 (1 mg/kg; p.o.)treatment shows the F% value is 53%.Animal Model:Rat?
Dosage:1 mg/kg
Administration:i.v. administration?(Pharmacokinetic?Analysis)
Result:The?Cl and?t1/2?were 0.13 L/h/kg and?3?hours,?respectively.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备