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编 号:F715057
分子式:C24H39ClN4O3S
分子量:499.11
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生物活性:
AT-121 hydrochloride is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3.67 and 16.49 nM, respectively. AT-121 hydrochloride is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects.

体内研究:
AT-121 hydrochloride (0.003-0.03 mg/kg; s.c.) produces potent antinociceptive effect.Animal Model:Adult male and female rhesus monkeys
Dosage:0.003-0.03 mg/kg
Administration:Subcutaneous
Result:Produced antinociceptive effects against an acute noxious stimulus, 50 °C water, in a dose-dependent.
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