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编 号:F714957
分子式:C14H23N7O6
分子量:385.38
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PD1-PDL1-IN 1 (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator.

体外研究:
PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance.
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