产品
编 号：F708001
分子式：C21H20F3N3O2
分子量：403.4
分子式：C21H20F3N3O2
分子量：403.4
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 1800296-63-2
产品详情
生物活性：
DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway.
体内研究：
DHODH-IN-1 (compound 18d) has a t1/2 of 27–41 min.
体外研究：
DHODH-IN-1 (compound 18d) strongly inhibits Jurkat cells proliferation (IC50=0.02 μM). DHODH-IN-1 (4, 20, 100 nM) blocks the measles virus replication in cells. DHODH-IN-1 (0.008, 0.04, 0.2, 1, 5 μM) increases the expression of an ISRE-luciferase reporter gene when transfecting cells with ssRNA molecules.
DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway.
体内研究：
DHODH-IN-1 (compound 18d) has a t1/2 of 27–41 min.
体外研究：
DHODH-IN-1 (compound 18d) strongly inhibits Jurkat cells proliferation (IC50=0.02 μM). DHODH-IN-1 (4, 20, 100 nM) blocks the measles virus replication in cells. DHODH-IN-1 (0.008, 0.04, 0.2, 1, 5 μM) increases the expression of an ISRE-luciferase reporter gene when transfecting cells with ssRNA molecules.
产品资料
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