产品
编 号：F706255
分子式：C17H25N3O2
分子量：303.4
分子式：C17H25N3O2
分子量：303.4
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CAS No: 175553-48-7
产品详情
生物活性：
Butabindide (UCL-1397) is a potent, selective tripeptidvl peptidase II (TPP II) inhibitor with Ki values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide inhibits TPP II to protect CCK-8 against inactivation.
体内研究：
Butabindide (UCL-1397; 10 mg/kg; i.v.; for 20 min) inhibits the breakdown of CCK-8 in the gastrointestinal tract and increases satiety in mice.Animal Model:Mice (25-30 g)
Dosage:10 mg/kg
Administration:Intravenous injection; for 20 minutes
Result:Reduces food intake and elicits other behavioral concomitants of satiation.
体外研究：
Butabindide (UCL-1397; 0-24 nM; membranes of rat cerebral cortex) inhibits TPP II activity of cerebral membranes.
Butabindide (UCL-1397) is a potent, selective tripeptidvl peptidase II (TPP II) inhibitor with Ki values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide inhibits TPP II to protect CCK-8 against inactivation.
体内研究：
Butabindide (UCL-1397; 10 mg/kg; i.v.; for 20 min) inhibits the breakdown of CCK-8 in the gastrointestinal tract and increases satiety in mice.Animal Model:Mice (25-30 g)
Dosage:10 mg/kg
Administration:Intravenous injection; for 20 minutes
Result:Reduces food intake and elicits other behavioral concomitants of satiation.
体外研究：
Butabindide (UCL-1397; 0-24 nM; membranes of rat cerebral cortex) inhibits TPP II activity of cerebral membranes.
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