产品
编 号：F703177
分子式：C21H27N3O3
分子量：369.46
分子式：C21H27N3O3
分子量：369.46
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CAS No: 1679371-59-5
产品详情
生物活性：
BMT-124110 is a potent, selective AAK1 inhibitor with an IC50 of 0.9 nM. BMT-124110 shows antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 17 and 99 nM, respectively.
体内研究：
BMT-124110 is added directly onto the spinal corevd by microiontophoresis, leading to reduction in windup-induced activity in 10 of 14 animals.
体外研究：
BMT-124110 shows a cellular IC50 of 3.2±1.4 nM for AAK1.
BMT-124110 is a potent, selective AAK1 inhibitor with an IC50 of 0.9 nM. BMT-124110 shows antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 17 and 99 nM, respectively.
体内研究：
BMT-124110 is added directly onto the spinal corevd by microiontophoresis, leading to reduction in windup-induced activity in 10 of 14 animals.
体外研究：
BMT-124110 shows a cellular IC50 of 3.2±1.4 nM for AAK1.
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