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编 号:F701709
分子式:C19H12N2O2
分子量:300.31
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration.
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