产品
编 号:F701709
分子式:C19H12N2O2
分子量:300.31
产品类型
结构图
CAS No: 1643120-60-8
联系客服
产品详情
生物活性:
YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration.