产品
编 号：F701116
分子式：C17H12ClN5OS
分子量：369.83
分子式：C17H12ClN5OS
分子量：369.83
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CAS No: 1630160-25-6
产品详情
生物活性：
ML338 is a selective small molecule inhibitor probe of non-replicating Mycobacterium tuberculosis bacilli?and is against the non-replicating?M. tuberculosis with IC90 and IC99 values of 1 μM and 4 μM, respectively by CFU. ML338 is a invaluable tool for identifying both essential functions and vulnerabilities of the?M. tuberculosis?bacilli in the nutrient deprivation states. ML338 can be used for the study of M. tuberculosis chemotherapy.
体外研究：
ML338 (0-50 μM) has potency and selectivity against non-replicating?M. tuberculosis with an IC90 of 1 μM. Additionally, ML338?have an IC99 against non-replicating?M. tuberculosis?(4 μM) which is excellent relative to current TB drugs.ML338? (0-50 μM; 48 hours) shows no toxicity to J774 macrophage cells up to 50 μM, the highest concentration.ML338?is against the non-replicating?M. tuberculosis with IC90 and IC99 velues of 1 μM and 4 μM, respectively by CFU. Additionally, it against the replicating?M. tuberculosis with IC90 and IC99 velues of 62 μM and 62 μM, respectively by CFU.
ML338 is a selective small molecule inhibitor probe of non-replicating Mycobacterium tuberculosis bacilli?and is against the non-replicating?M. tuberculosis with IC90 and IC99 values of 1 μM and 4 μM, respectively by CFU. ML338 is a invaluable tool for identifying both essential functions and vulnerabilities of the?M. tuberculosis?bacilli in the nutrient deprivation states. ML338 can be used for the study of M. tuberculosis chemotherapy.
体外研究：
ML338 (0-50 μM) has potency and selectivity against non-replicating?M. tuberculosis with an IC90 of 1 μM. Additionally, ML338?have an IC99 against non-replicating?M. tuberculosis?(4 μM) which is excellent relative to current TB drugs.ML338? (0-50 μM; 48 hours) shows no toxicity to J774 macrophage cells up to 50 μM, the highest concentration.ML338?is against the non-replicating?M. tuberculosis with IC90 and IC99 velues of 1 μM and 4 μM, respectively by CFU. Additionally, it against the replicating?M. tuberculosis with IC90 and IC99 velues of 62 μM and 62 μM, respectively by CFU.
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