产品
编 号：F700030
分子式：C21H16N4O2
分子量：356.38
分子式：C21H16N4O2
分子量：356.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1609583-14-3
产品详情
生物活性：
PF-06256142 is a potent, selective, CNS-penetrant and orally active agonist of the D1 receptor, with an EC50 and Ki of 33 nM and 12 nM, respectively. PF-06256142 has the potential for the research of schizophrenia and Parkinson's disease.
体内研究：
PF-06256142 exhibits high oral bioavailability (rat 85%) following oral administration (rat 5 mg/kg).PF-06256142 exhibits terminal elimination half-life (rat 2.3 h) following intravenous administration (rat 5.0 mg/kg).Animal Model:Rat
Dosage:5.0 mg/kg for i.v.; 5 mg/kg for oral (Pharmacokinetic Analysis)
Administration:Intravenous injection and oral administration
Result:Oral bioavailability (85%), T1/2 (2.3 h).
体外研究：
PF-06256142 exhibits IC50 values of 10 μM).
PF-06256142 is a potent, selective, CNS-penetrant and orally active agonist of the D1 receptor, with an EC50 and Ki of 33 nM and 12 nM, respectively. PF-06256142 has the potential for the research of schizophrenia and Parkinson's disease.
体内研究：
PF-06256142 exhibits high oral bioavailability (rat 85%) following oral administration (rat 5 mg/kg).PF-06256142 exhibits terminal elimination half-life (rat 2.3 h) following intravenous administration (rat 5.0 mg/kg).Animal Model:Rat
Dosage:5.0 mg/kg for i.v.; 5 mg/kg for oral (Pharmacokinetic Analysis)
Administration:Intravenous injection and oral administration
Result:Oral bioavailability (85%), T1/2 (2.3 h).
体外研究：
PF-06256142 exhibits IC50 values of 10 μM).
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备