产品
编 号:F697841
分子式:C30H46N4O4
分子量:526.71
产品类型
结构图
CAS No: 157207-90-4
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产品详情
生物活性:
Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effcts. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs).
体外研究:
Hemiasterlin is an antimitotic agent by disrupting microtubule dynamics causing mitotic arrest and cell death with low- to sub-nanomolar potencies against several cancer cell lines.