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编 号:F691006
分子式:C32H31N3O8
分子量:585.6
产品类型
结构图
CAS No: 1473403-87-0
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生物活性:
MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks.