产品
编 号：F690579
分子式：C30H44N2O9S2
分子量：640.81
分子式：C30H44N2O9S2
分子量：640.81
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CAS No: 146697-04-3
产品详情
生物活性：
Thiomarinol A (4-Hydroxythiomarinol C) is a potent antibiotic. Thiomarinol A is a hybrid of dithiolopyrrolone and marinolic acid. Thiomarinol A shows antimicrobial activity. Thiomarinol A inhibits MRSA IleRS in a dose-dependent with a Kiapp value of 19 nM.
体外研究：
Thiomarinol A shows antimicrobial activity with MICs of 0.002, 0.08, 0.04, 0.04, 0.50, 0.02, 0.01 μM for COL IleRS, LLMR COL IleRSV588F/V631F, LLMR COL IleRSF587V/V631F, LLMR COL IleRSV588F, IleRSV588F MupA, thiomarinol-resistant COL IleRSG593D, thiomarinol-resistant COL IleRSP606S, respectively.
Thiomarinol A (4-Hydroxythiomarinol C) is a potent antibiotic. Thiomarinol A is a hybrid of dithiolopyrrolone and marinolic acid. Thiomarinol A shows antimicrobial activity. Thiomarinol A inhibits MRSA IleRS in a dose-dependent with a Kiapp value of 19 nM.
体外研究：
Thiomarinol A shows antimicrobial activity with MICs of 0.002, 0.08, 0.04, 0.04, 0.50, 0.02, 0.01 μM for COL IleRS, LLMR COL IleRSV588F/V631F, LLMR COL IleRSF587V/V631F, LLMR COL IleRSV588F, IleRSV588F MupA, thiomarinol-resistant COL IleRSG593D, thiomarinol-resistant COL IleRSP606S, respectively.
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