产品
编 号：F687443
分子式：C32H37N3O4S
分子量：559.72
分子式：C32H37N3O4S
分子量：559.72
产品类型
规格
价格
是否有货
结构图
CAS No: 1423067-48-4
产品详情
生物活性：
(Rac)-BI 703704 is a potent soluble guanylyl cyclase (sGC) activator. (Rac)-BI 703704 reduces progression of renal damage in the ZSF1 rat, and highlight the potential of sGC activation as an effective therapy for diabetic nephropathy.
体内研究：
(Rac)-BI 703704 (0.3-10 mg/kg; food intake; daily for 15 weeks) inhibits the progression of diabetic nephropathy in the ZSF1 rat.Animal Model:12-13 weeks male ZSF1 obese rats
Dosage:0.3, 1, 3, or 10 mg/kg
Administration:Food intake; daily for 15 weeks
Result:Dose-dependent increased in renal cGMP levels; Dosedependent decreased in urinary protein excretion (UPE); Accompanied by a significant reduction in the incidence of glomerulosclerosis and interstitial lesions.
(Rac)-BI 703704 is a potent soluble guanylyl cyclase (sGC) activator. (Rac)-BI 703704 reduces progression of renal damage in the ZSF1 rat, and highlight the potential of sGC activation as an effective therapy for diabetic nephropathy.
体内研究：
(Rac)-BI 703704 (0.3-10 mg/kg; food intake; daily for 15 weeks) inhibits the progression of diabetic nephropathy in the ZSF1 rat.Animal Model:12-13 weeks male ZSF1 obese rats
Dosage:0.3, 1, 3, or 10 mg/kg
Administration:Food intake; daily for 15 weeks
Result:Dose-dependent increased in renal cGMP levels; Dosedependent decreased in urinary protein excretion (UPE); Accompanied by a significant reduction in the incidence of glomerulosclerosis and interstitial lesions.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备