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编 号：F686960
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CAS No: 1414-39-7
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Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer.
体外研究：
Albomycin 也与 FhuA 结合，与高铁色素竞争结合位点。FhuA 是埋在大肠杆菌外膜的 β 桶。或者，Albomycin 结合 FhuD，FhuD 是细胞膜 ABC 转运蛋白 FhuB/FhuC 的质周亚基。Albomycin 对肺炎链球菌的生长有明显的抑制作用，最低抑制浓度为 4-62 nM。
Albomycin is an inhibitor of aminoacyl-tRNA synthetases with Trojan-horse effect. Albomycin is delivered by iron-chelator portion into bacterial through ferrichrome-specific transporter system. Albomycin combats against a wide range of Gram-positive and Gram-negative bacteria. Albomycin also serves as an efficient iron-scavenger of producer.
体外研究：
Albomycin 也与 FhuA 结合，与高铁色素竞争结合位点。FhuA 是埋在大肠杆菌外膜的 β 桶。或者，Albomycin 结合 FhuD，FhuD 是细胞膜 ABC 转运蛋白 FhuB/FhuC 的质周亚基。Albomycin 对肺炎链球菌的生长有明显的抑制作用，最低抑制浓度为 4-62 nM。
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