产品
编 号:F068196
分子式:C14H9FN4O
分子量:268.25
产品类型
结构图
CAS No: 1201323-97-8
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产品详情
生物活性:
MK-3328 is a β-Amyloid PET ligand, which exhibits high binding potency with an IC50 of 10.5 nM.
体内研究:
In vivo, [18F]MK-3328 demonstrates favorable kinetics, exhibiting high brain uptake and good washout in normal rhesus monkey positron emission tomography (PET) imaging studies.
体外研究:
MK-3328 exhibits amyloid binding potency balanced with low levels of nonspecific binding.