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编 号:F680590
分子式:C18H20N2O4S
分子量:360.43
产品类型
结构图
CAS No: 1331745-61-9
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生物活性:
ML372 inhibits survival motor neuron (SMN) protein ubiquitination, increases SMN protein stability without affecting mRNA expression. ML372 improves spinal muscular atrophy (SMA) in mice. ML372 is brain penetrant and has a reasonable exposure and half-life in vivo.